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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AP2A2
All Species:
41.52
Human Site:
Y53
Identified Species:
83.03
UniProt:
O94973
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O94973
NP_036437.1
939
103960
Y53
G
D
K
A
L
D
G
Y
S
K
K
K
Y
V
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001116794
953
104990
H51
G
H
D
I
D
F
G
H
M
E
A
V
N
L
L
Dog
Lupus familis
XP_533200
1007
111388
Y125
G
D
K
A
L
D
G
Y
S
K
K
K
Y
V
C
Cat
Felis silvestris
Mouse
Mus musculus
P17427
938
104082
Y53
G
D
K
A
L
D
G
Y
S
K
K
K
Y
V
C
Rat
Rattus norvegicus
P18484
938
104026
Y53
G
D
K
A
L
D
G
Y
S
K
K
K
Y
V
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012914
938
104174
Y53
G
D
K
A
L
D
G
Y
S
K
K
K
Y
V
C
Frog
Xenopus laevis
NP_001089303
939
104392
Y53
G
D
K
A
L
D
G
Y
S
K
K
K
Y
V
C
Zebra Danio
Brachydanio rerio
XP_001922436
930
103267
Y53
G
D
K
A
L
D
G
Y
S
K
K
K
Y
V
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91926
940
105602
Y52
G
D
K
T
L
D
G
Y
Q
K
K
K
Y
V
C
Honey Bee
Apis mellifera
XP_394621
937
104937
Y52
G
D
K
T
L
D
G
Y
Q
K
K
K
Y
V
C
Nematode Worm
Caenorhab. elegans
NP_509572
925
104161
Y52
G
D
K
T
L
D
G
Y
Q
K
K
K
Y
V
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P38065
1025
114993
Y69
N
H
D
R
L
G
G
Y
Q
R
K
K
Y
V
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
93.6
89.3
N.A.
97.2
97.2
N.A.
N.A.
95.3
87.6
84.3
N.A.
69.8
71
66.1
N.A.
Protein Similarity:
100
N.A.
94.5
91.3
N.A.
98.6
98.8
N.A.
N.A.
97.7
94.2
91.1
N.A.
81.4
82.2
78.4
N.A.
P-Site Identity:
100
N.A.
13.3
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
86.6
86.6
86.6
N.A.
P-Site Similarity:
100
N.A.
33.3
100
N.A.
100
100
N.A.
N.A.
100
100
100
N.A.
86.6
86.6
86.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
25.3
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
45.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
59
0
0
0
0
0
0
9
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
84
% C
% Asp:
0
84
17
0
9
84
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
92
0
0
0
0
9
100
0
0
0
0
0
0
0
0
% G
% His:
0
17
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
84
0
0
0
0
0
0
84
92
92
0
0
0
% K
% Leu:
0
0
0
0
92
0
0
0
0
0
0
0
0
9
9
% L
% Met:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% M
% Asn:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
34
0
0
0
0
0
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
59
0
0
0
0
0
0
% S
% Thr:
0
0
0
25
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
9
0
92
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
92
0
0
0
0
92
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _